Vitamin D
cofactor
Summary
Vitamin D is a group of fat-soluble prohormones, the two major forms of which are vitamin D2 (or ergocalciferol) and vitamin D3 (or cholecalciferol). The term vitamin D also refers to metabolites and other analogues of these substances. Vitamin D3 is produced in skin exposed to sunlight, specifically ultraviolet B radiation.
“Vitamin D - Wikidoc.” Wikidoc.org, 2013, www.wikidoc.org/index.php/Vitamin_D
Benefits
1.
promotes the activation of tyrosine hydroxylase, an essential enzyme in the synthesis of dopamine and noradrenaline [1][3]
2.
activates serotonin production [2]
Deficiency Factors
vegan diet, lack of sun exposure
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Applications & Precautions
ApplicationsInsomnia
Precautions
Excessive vitamin D supplementation without adequate vitamin K (from diet or supplementation) may contribute to atherosclerosis (hardening of the arteries) [3]. The most common sign of 'vitamin D overload' is oily hair or skin.
Important Notes
Being that vitamin D is a fat-soluble vitamin (and can be stored), a single daily dose can be administered rather than multiple {smaller) doses.
Dosage Guidelines
2000
6000
IU
2000
IU
10000
IU
with food
Recommended Products
Vitamin D-3 2,000 IU - NOW
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Vitamin D3 5000 IU Softgels - Blue Bonnet
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References
1.
Trinko, Joseph R., et al. “Vitamin D3: A Role in Dopamine Circuit Regulation, Diet-Induced Obesity, and Drug Consumption.” Eneuro, vol. 3, no. 3, May 2016, pp. ENEURO.0122-15.2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4875352/, 10.1523/eneuro.0122-15.2016.
2.
Patrick, Rhonda P., and Bruce N. Ames. “Vitamin D and the Omega‐3 Fatty Acids Control Serotonin Synthesis and Action, Part 2: Relevance for ADHD, Bipolar Disorder, Schizophrenia, and Impulsive Behavior.” The FASEB Journal, vol. 29, no. 6, 24 Feb. 2015, pp. 2207–2222, pubmed.ncbi.nlm.nih.gov/25713056/, 10.1096/fj.14-268342.
3.
Kim, Sang-Hyun, et al. “Relationship between Serum Vitamin D Levels and Symptoms of Depression in Stroke Patients.” Annals of Rehabilitation Medicine, vol. 40, no. 1, 2016, p. 120, www.ncbi.nlm.nih.gov/pmc/articles/PMC4775744/, 10.5535/arm.2016.40.1.120.
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