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Vitamin B12
 
cofactor
Summary

"Vitamin B12 or cobalamin plays essential roles in folate metabolism and in the synthesis of the citric acid cycle intermediate, succinyl-CoA...Vitamin B12 is essential for the preservation of the myelin sheath around neurons and for the synthesis of neurotransmitters."

- “Vitamin B12.” Linus Pauling Institute, 22 Apr. 2014, lpi.oregonstate.edu/mic/vitamins/vitamin-B12.

Benefits
1.
supports optimal levels of dopamine, noradrenaline, and serotonin as a synthesis cofactor [1]
Deficiency Factors
alcohol consumption, dietary insufficiency, vegan diet, vegetarian diet, other supplements

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Applications & Precautions
Applications
Alcohol Detox
Precautions
Excessive B12 supplementation may cause nervousness and/or restlessness.
Dosage Guidelines
Dosing Range
1000
-
2000
mcg
Dose Increment
1000
mcg
Maximum Daily
4000
mcg
Best absorbed
with food
Recommended Products
Methyl B-12 1000 mcg - Blue Bonnet Order from Amazon 
Vitamin B12 2000 mcg - Nutricost Order from Amazon 

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References
1. 
R;Vincenti, Deana. “Levels of Neurotransmitters in Brain of Vitamin B12 Deficient Rats.” International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition, vol. 47, no. 2, 2011, pubmed.ncbi.nlm.nih.gov/18422/, . Accessed 16 June 2021.
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These icons appear on items to indicate the affected neurotransmitter(s).
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Dopaminergic. promotes the synthesis or activity of dopamine.

Endorphinergic. promotes the synthesis or activity of endorphins.

noradrenergic

Noradrenergic. promotes the synthesis or activity of noradrenaline.

Cholinergic. promotes the synthesis or activity of acetylcholine.

gabanergic

GABAnergic. promotes the synthesis or activity of GABA.

Serotonergic. promotes the synthesis or activity of serotonin.

These icons appear on items to indicate the optimal time-of-day.
rising

Rising. sunrise to mid-morning.

2-midmorning

Morning. mid-morning to noon.

3-noon

Noon. noon to mid-afternoon.

5-sunset

Afternoon. mid-afternoon to sunset.

evening

Evening. sunset to bedtime.

These icons appear on items to indicate additional benefits & important alerts.

Synergistic. combining with another supplement may increase potency.

Methylation agent. increases or decreases methylation of neurotransmitters.

Cortisol modulator. affects the synthesis or activity of the stress hormone cortisol.

Glucose regulator. attenuates changes in blood sugar levels.

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Achievements

Neurotransmitter Scores

Dopamine

 

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Endorphin

 

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Noradrenaline

 

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Acetylcholine

 

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GABA

 

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Serotonin

 

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Member Since
Achievements

Neurotransmitter Scores

Dopamine

 

??

Endorphin

 

??

Noradrenaline

 

??

Acetylcholine

 

??

GABA

 

??

Serotonin

 

??

Go to Results