Skip to content
SEG logo

supplements

DLPA
 
precursor
Summary

"DL-Phenylalanine is marketed as a nutritional supplement for its putative analgesic and antidepressant activities. The putative analgesic activity of DL-phenylalanine may be explained by the possible blockage by D-phenylalanine of enkephalin degradation by the enzyme carboxypeptidase A. The mechanism of DL-phenylalanine's putative antidepressant activity may be accounted for by the precursor role of L-phenylalanine in the synthesis of the neurotransmitters norepinephrine and dopamine."

“Phenylalanine - Wikidoc.” Wikidoc.org, 2022, www.wikidoc.org/index.php/Phenylalanine.

‌

Benefits
1.
increases beta-endorphin levels by blocking the degradation enzyme, carboxypeptidase A. [1]
2.
may increase available dopamine by providing the first-stage precursor phenylalanine. [2]
3.
may reduce withdrawal symptoms from addictive substances by inhibiting endorphin breakdown [3]
Deficiency Factors
dietary insufficiency

Access a list of other supplements that enhance the benefits of [vg_display_data key=”post_title” data_source=”post_data”] when you signup for a support plan.

Applications
Alcohol Detox, Burnout, Sugar Detox
Dosage Guidelines
Dosing Range
500
-
1500
mg
Dose Increment
500
mg
Maximum Daily
6000
mg
Best absorbed
without food
Recommended Products
DLPA DL-Phenylalanine 375 mg - Source Naturals Order from Amazon 
D L-Phenylalanine 500 mg - Life Extension Order from Amazon 

See a list of verified product recommendations for [vg_display_data key=”post_title” data_source=”post_data”] when you signup for a support plan.

Add to Supplement Stack
add to supplement stack
add to supplement stack
Add Auxiliary Schedule
References
1. 
Walsh. “Analgesic Effectiveness of D-Phenylalanine in Chronic Pain Patients.” Archives of Physical Medicine and Rehabilitation, vol. 67, no. 7, 2021, pubmed.ncbi.nlm.nih.gov/3524509/.
2. 
Nutrient Metabolism. Elsevier, 2003, www.sciencedirect.com/book/9780124177628/nutrient-metabolism.
3. 
Blum, Kenneth, et al. “Hypothesizing Balancing Endorphinergic and Glutaminergic Systems to Treat and Prevent Relapse to Reward Deficiency Behaviors: Coupling D-Phenylalanine and N-Acetyl-L-Cysteine (NAC) as a Novel Therapeutic Modality.” Clinical Medical Reviews and Case Reports, vol. 2, no. 12, 31 Dec. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4760695/, https://doi.org/10.23937/2378-3656/1410076.
Legend

Shopping cart

Signup for the free Stress & Energy Guide to discover the supplements for your neurochemistry, save your results, and more!
Learn More
Schedule Added!

Refresh the page to see your selection in the auxiliary schedule. Use the time-of-day tabs to navigate between schedules.

Refresh
These icons appear on items to indicate the affected neurotransmitter(s).
Created with Fabric.js 4.6.0

Dopaminergic. promotes the synthesis or activity of dopamine.

Endorphinergic. promotes the synthesis or activity of endorphins.

noradrenergic

Noradrenergic. promotes the synthesis or activity of noradrenaline.

Cholinergic. promotes the synthesis or activity of acetylcholine.

gabanergic

GABAnergic. promotes the synthesis or activity of GABA.

Serotonergic. promotes the synthesis or activity of serotonin.

These icons appear on items to indicate the optimal time-of-day.
rising

Rising. sunrise to mid-morning.

2-midmorning

Morning. mid-morning to noon.

3-noon

Noon. noon to mid-afternoon.

5-sunset

Afternoon. mid-afternoon to sunset.

evening

Evening. sunset to bedtime.

These icons appear on items to indicate additional benefits & important alerts.

Synergistic. combining with another supplement may increase potency.

Methylation agent. increases or decreases methylation of neurotransmitters.

Cortisol modulator. affects the synthesis or activity of the stress hormone cortisol.

Glucose regulator. attenuates changes in blood sugar levels.

Johnathan Kobé
Founder
Learn how you can overcome burnout, fuel your creativity, and find your focus to make great ideas take off!
Discover how to master your mood & mental attitude with reliable solution to stress & energy.
Signup for 3 short introduction videos. Unsubscribe anytime.
Johnathan Kobé
Founder - DREAM BIG
Learn how you can overcome burnout, fuel your creativity, and find your focus with the DREAM BIG Program.
Discover how the DREAM BIG Program can help you master your mood & mental attitude.
Signup for 3 short introduction videos. Unsubscribe anytime.
Welcome
Hello there
Your results are in! Your dopamine score has been updated. You may now access your results.
enhance your images
Hello there
Leverage agile frameworks to provide a robust synopsis for high level overviews.
discover Images
Hello there
Leverage agile frameworks to provide a robust synopsis for high level overviews.
Member Since
Achievements

Neurotransmitter Scores

Dopamine

 

??

Endorphin

 

??

Noradrenaline

 

??

Acetylcholine

 

??

GABA

 

??

Serotonin

 

??

Go to Results
Member Since
Achievements

Neurotransmitter Scores

Dopamine

 

??

Endorphin

 

??

Noradrenaline

 

??

Acetylcholine

 

??

GABA

 

??

Serotonin

 

??

Go to Results
The Alcohol Detox Protocol
Enter your email address and we will send you a copy of the Alcohol Detox Protocol. Start your journey today!
Free for a Limited Time
Rinse & Replace
Enter your email and we will send you a copy of the Alcohol Detox Protocol.
Free for a Limited Time
The Alcohol Detox Protocol
Rinse & Replace
Start your journey today!