Vitamin B6
cofactor
Summary
Vitamin B6 is a water-soluble vitamin. Pyridoxal phosphate (PLP) is the active form and is a cofactor in many reactions of amino acid metabolism, including transamination, deamination, and decarboxylation. PLP also is necessary for the enzymatic reaction governing the release of glucose from glycogen.
“Vitamin B6 - Wikidoc.” Wikidoc.org, 2022, www.wikidoc.org/index.php/Vitamin_B6
Benefits
1.
supports optimal levels of dopamine, GABA, and serotonin as a synthesis cofactor. [1]
Deficiency Factors
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Applications & Precautions
Important Notes
Vitamin B6 intake has a biphasic effect, whereby both deficient and excessive amounts deplete several neurotransmitters. The effective dose range seems to be between 1x and 100x the RDI. [2]
Dosage Guidelines
50
100
mg
50
mg
100
mg
with food
Recommended Products
Kal 50 Mg B-6 Pyridoxal-5-phosphate Tablets - KAL
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Pyridoxal 5-Phosphate 100 mg - Monoherb
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References
1.
Kennedy, David. “B Vitamins and the Brain: Mechanisms, Dose and Efficacy—a Review.” Nutrients, vol. 8, no. 2, 27 Jan. 2016, p. 68, www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/, 10.3390/nu8020068.
2.
Schaeffer, Monica C., et al. “Dietary Excess of Vitamin B-6 Affects the Concentrations of Amino Acids in the Caudate Nucleus and Serum and the Binding Properties of Serotonin Receptors in the Brain Cortex of Rats.” The Journal of Nutrition, vol. 128, no. 10, 1 Oct. 1998, pp. 1829–1835, academic.oup.com/jn/article/128/10/1829/4723060?login=false, 10.1093/jn/128.10.1829.
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